Abstract Increasing evidence indicates that Nrf-2, named the nuclear factor-erythroid 2-related factor, may perform anticancer function.In this study, a series of novel substituted phenyl- (3-methyl-1H-indol-2-yl)-prop-2-en-1-one (indolyl-chalcone) derivatives were synthesized and their effects on Nrf-2 Trim / Bezel / Surrounds activity were observ
MIGRATION CRISIS IN THE EU: IS THE PEAK PASSED?
The article analyses the prospects of a new migration crisis in the European Union.Referring the statistics of displaced persons within Afghanistan and the neighboring countries, the author predicts potential threat of an emergency migration influx to Europe.The factors are proposed that can cause a significant outflow of population from the countr
Harmonic Distortion Minimization in Power Grids with Wind and Electric Vehicles
Power-electronic interfacing based devices such as wind generators (WGs) and electrical vehicles (EVs) cause harmonic distortions on the power grid.Higher penetration and uncoordinated operation of WGs and EVs can lead to voltage and current harmonic distortions, which may Vinpocetine exceed IEEE limits.It is interesting to note that WGs and EVs ha